Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Women with Multiple Sclerosis (between 18-55 years old) who have lower urinary symptoms such as urgency, frequency and nacturia with detrusor sphincter dyssynergia or over active bladder refractory to drug therapy (treatment of at least three months with one or two anticholinergic drugs) are included in study. The exclusion criteria are: urinary infection; previous urogenital surgery; renal stone; pregnancy; severe cardiopulmonary diseases; physical inability; diabetes mellitus; other central nervous system diseases. Also, patients who don’t consent do not consider. When the urinary symptoms aggravate, attack of multiple sclerosis appear or weekly treatment are not followed, the patients are also removed from the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum-systometric-capacity. Timepoint: Before and after intervention. Method of measurement: Urodynamic study.;Involuntary detrusor contraction volume. Timepoint: Before and after intervention. Method of measurement: Urodynamic study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency. Timepoint: In each refering. Method of measurement: Ask from the patients.;Nacturia. Timepoint: In each refering. Method of measurement: Ask from the patients.;PVR. Timepoint: Before and after of stimulation. Method of measurement: Nelaton Catheter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences