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Dutasteride and Pumkin seed oil loaded nanostructured lipid carrier(NLC) in angrogenic alopecia

Comparison of efficacy and safety of nanostructured lipid carriers loaded with Dutasteride and pumpkin seed oil and oily solution containing Dutasteride and pumpkin seed oil for androgenic hair loss pattern

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130313012810N52
Enrollment
24
Registered
2025-02-15
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic Alopecia.

Interventions

Intervention 1: Intervention group: The first group will take nanostructured lipid carriers containing dutasteride and pumpkin seed oil on the forehead every three days for six months. Intervention 2:

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Male volunteers diagnosed with mild to moderate androgenic alopecia Be between 20-70 years old People who agreed to the informed consent form

Exclusion criteria

Exclusion criteria: Receiving any prescription of finasteride and its anti-androgen effect 8 weeks before starting dutasteride History of malignancy other than non-melanotic cancers Any diagnosis of global hair thinning or any other scalp or hair disease History of infertility and varicocele Concomitant use of corticosteroids, anabolic steroids, or over-the-counter "hair restorers." Light or laser treatment of the scalp in the last 3 months Previous correction of hair loss surgery Scars, sensitivity and local infections in the scalp

Design outcomes

Primary

MeasureTime frame
Hair growth and hair density of area. Timepoint: Measurement of hair growth at the beginning, 3 and 6 months after the start of the study. Method of measurement: Questionnaire, Head imaging and Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Hamishehkar

Tabriz University of Medical Sciences

hamishehkar.hamed@gmail.com+98 41 3336 3181

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026