effect of Dexamethasone on postoperative pain in congenital urethral defects

The effect of 0.2 mg/kg Dexamethasone on reducing pain in children after hypospadias surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130311012782N63

Enrollment

Registered

2025-02-02

Start date

2025-04-04

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypospadias. Hypospadias, unspecified

Interventions

Intervention 1: Intervention group: Receiving 0.2 mg/kg of dexamethasone by slow intravenous injection immediately after induction of anesthesia. Intervention 2: Control group: Receiving normal saline

Eligibility

Sex/Gender

Male

Age

1 Years to 8 Years

Inclusion criteria

Inclusion criteria: Age range: 1 to 8 years ASA class 1 and 2 Elective surgery Consent of the patient's legal guardian to participate in the study

Exclusion criteria

Exclusion criteria: The presence of underlying diseases, including respiratory, cardiovascular, and diabetes diseases

Design outcomes

Primary

Measure	Time frame
Postoperative pain. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: By Ocher Visual Analog Scale.;Systolic blood pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Pulse oximeter.;Blood oxygen saturation percentage. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.;Restlessness. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Richmond Score.;Diastolic Blood pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.;Mean arterial Blood Pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.	—

Measure

Time frame

Postoperative pain. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: By Ocher Visual Analog Scale.;Systolic blood pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Pulse oximeter.;Blood oxygen saturation percentage. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.;Restlessness. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Richmond Score.;Diastolic Blood pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.;Mean arterial Blood Pressure. Timepoint: Every 15 minutes during recovery and 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Monitoring machine.

—

Secondary

Measure	Time frame
Length of stay in recovery. Timepoint: When the patient leaves recovery. Method of measurement: Time interval between patient entry and exit from recovery.;Patient's parents' satisfaction. Timepoint: Patient discharge time. Method of measurement: 5-point Likert scale (completely satisfied, satisfied, neutral, dissatisfied, completely dissatisfied).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Esfahan University of Medical Sciences

amir_shafa@med.mui.ac.ir+98 31 3669 2174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026