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The effect of endometrial abrasion in both follicular and luteal stages on fertility success by intrauterine sperm injection

Comparison effect of endometrial abrasion on the success of intrauterine sperm injection in both follicular and luteal phases in infertile women with unexplained infertility

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130311012782N48
Enrollment
75
Registered
2020-06-15
Start date
2020-08-22
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unexplained infertility. Female infertility, unspecified

Interventions

Intervention 1: Intervention group 1: Uterine abrasion between days 19 and 24 of the menstrual cycle before intrauterine injection of sperm and in the luteal phase. Intervention 2: Intervention group

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 38 Years

Inclusion criteria

Inclusion criteria: Range age between 21-38 years old Body Mass Index between 18.5-29.9 kg/m2 Levels of thyroid stimulating hormone less than 10 meq/ml in 2 to 3 days Normal thyroid condition Bilateral opening of fallopian tubes in HSG or laparoscopy

Exclusion criteria

Exclusion criteria: Existence of adnexal mass in transvaginal ultrasound Normal analysis of Semen liquid with a volume of 2-5 ml with a concentration of more than 20 million / ml Total sperm motility more than 50% Natural sperm form more than 30% husband with severe infertility Stages 3 and 4 endometriosis Infertility due to defects in the fallopian tubes Abnormal thyroid hormone or prolactin levels Uterine fibroids or severe systemic or infectious disease

Design outcomes

Primary

MeasureTime frame
Fertility success. Timepoint: 6 months after intervention. Method of measurement: Measurement of beta HCg and vaginal ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Ghaed Amini

Esfahan University of Medical Sciences

ghaedamini@gmail.com+98 21 3236 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026