effect of adding Cyprofloxacin ointment in treatment of Lishmaniasis

Study of the additional effect of topical ciprofloxacin on intralesional injection of glucantime in the treatment of cutaneous leismaniasis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130311012782N46

Enrollment

Registered

2020-05-25

Start date

2020-08-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous Lishmaniasis. Cutaneous leishmaniasis

Interventions

Intervention 1: Intervention group: In this group treated with topical ointment ciprofloxacin liposomes twice a day with a weekly injection of glucocorticoids into the lesion for 8 weeks. Then the siz

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Having a Lishmaniasi with direct smear confirmation The clinical course of the lesion is less than 6 months No history of leishmaniasis treatment 2 months before entering the study

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Use of other therapies during the study period Specific forms of leishmaniasis, such as erysipeloid, zosteriform, vasoprotective, and lopoid

Design outcomes

Primary

Measure	Time frame
Improvement status. Timepoint: Every week for 8 weeks. Method of measurement: Physical examination.;Improvement time. Timepoint: Every week for 8 weeks. Method of measurement: Physical examination.;Size of scare. Timepoint: Ent of treatment. Method of measurement: Physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Yazdanpanah

Mashhad University of Medical Sciences

yazdanpanahmj@mums.ac.ir+98 51 3669 2174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026