Effect of tranexamic acid and remifentanil on intraoperative hemorrhage in dacryocystorhinostomy

Comparison of the effect of tranexamic acid and remifentanil on intraoperative hemorrhage in dacryocystorhinostomy and comparing with control group

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130311012782N42

Enrollment

165

Registered

2020-03-03

Start date

2019-07-16

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dacryocystorhinostomy. Stenosis of unspecified lacrimal canaliculi

Interventions

Intervention 1: Intervention group: receiving bolus of tranexamic acid 15 mg / kg in a 15-minute period with 500 ml of normal saline. Intervention 2: Intervention group: receiving remifentanil infusio

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients candidate for classic dacryocystorhinostomy surgery Age range between 18 and 75 years No sensitivity to drugs No coagulation problems No addiction No chronic underlying disease

Exclusion criteria

Exclusion criteria: Changing the anesthesia procedure

Design outcomes

Primary

Measure	Time frame
Intraoperative bleeding. Timepoint: From the beginning of the operation to the end of the operation. Method of measurement: The volume of blood suctioned per ml.	—

Secondary

Measure	Time frame
Hemodynamic Disorder. Timepoint: Every 15 minutes during operation and recovery. Method of measurement: Pulse oximetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran Montazeri

Esfahan University of Medical Sciences

montazeri@med.mui.ac.ir+98 31 3669 2174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026