Comparison of the effect of two drugs Midazolam and Dexmedetumidine on vital signs and postoperative complications

Comparison effect of Midazolam and Dexmedtomidin , on hemodynamic changes during surgery and post operative complication in the surgery of Permcath implantation

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130311012782N35

Enrollment

Registered

2019-09-10

Start date

2019-09-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative complicaqtions.

Interventions

Intervention 1: Intervention group: group of receive 0.1 micgr/kg intravenously Dexmedetomidine made by Exire company, during 10 minutes immediately after induction. Intervention 2: Intervention group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range of 65-18 years old American Society of Anesthesiologists (ASA) score of II and III Patient agrees to participate in the study

Exclusion criteria

Exclusion criteria: Receiving drugs that affect hemodynamic status Receiving ?Anticoagulant drugs

Design outcomes

Primary

Measure	Time frame
Blood Pressure. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry, Observation.;Heart Rate. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry.;Blood Oxygen Saturation. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry.;Nausea. Timepoint: During stay of patients in recovery. Method of measurement: Observation.;Vomitting. Timepoint: During stay of patients in recovery. Method of measurement: Observation.	—

Measure

Time frame

Blood Pressure. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry, Observation.;Heart Rate. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry.;Blood Oxygen Saturation. Timepoint: In every 10 minutes during surgery and recovery. Method of measurement: Pulse oximetry.;Nausea. Timepoint: During stay of patients in recovery. Method of measurement: Observation.;Vomitting. Timepoint: During stay of patients in recovery. Method of measurement: Observation.

—

Secondary

Measure	Time frame
Hemodynamic disorder. Timepoint: Every 10 minutes during surgery and recovery. Method of measurement: pulse oximetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Taghi Hashemi

Esfahan University of Medical Sciences

st_hashemi@med.mui.ac.ir+98 31 3669 2174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026