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Effect of Colchicine on secondary prevention of ischemic stroke

Evaluation the efficacy of colchicine on secondary prevention of ischemic stroke in patients with atrial fibrillation (AF)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130311012781N5
Enrollment
20
Registered
2020-08-25
Start date
2020-06-21
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke..

Interventions

Intervention 1: All patients will be treated wih the rivaroxaban at the appropriate of dose once daily for a year. Patients will be additionally treated with colchicine at the dose of 0.5 mg twice da

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are admitted with a diagnosis of ischemic stroke and have AF at the time of hospitalization The considered age group is 18 years or older

Exclusion criteria

Exclusion criteria: Allergies and sensitivities to colchicine Patients who are taking corticosteroids, methotrexate, TNFa-blockers, interleukin1 -1b antagonist Patients with inflammatory disease such as lupus, rheumatoid arthritis, connective tissue disease or chronic infections Patients with sever Renal failure ( GFR 2 above normal Patients with moderate to severe cytopenia (plt < 100000, neutrophil count < 1500) or blood dyscrasia Patients who are contraindicated for rivaroxaban Pregnant or lactating women or women in childbearing age who do not take appropriate contraception

Design outcomes

Primary

MeasureTime frame
Recurrence of stroke. Timepoint: 3, 6, 9 and 12 months after the beginning of study. Method of measurement: Clinical history and imaging finding.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDavood kashipazha

Ahvaz University of Medical Sciences

dakashi47@gmail.com+98 61 3374 3012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026