Diffuse traumatic brain injury. Diffuse traumatic brain injury
Conditions
Interventions
Intervention 1: Intervention group: Patients with Pure moderate-to-severe TBI (GCS: motor score < 6) and low normal TFT profile: T3 & T4 in first 25% of normal range + normal range of TSH, will receiv
Sponsors
Vice chancellor of research. Shiraz University of medical sciences
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: Pure moderate-to-severe TBI (GCS: motor score < 6) Low normal TFT profile: T3 & T4 in first 25% of normal range normal range of TSH
Exclusion criteria
Exclusion criteria: Mild traumatic brain injury Patients with a pituitary abnormality on pituitary imaging Patients who were unwilling to participate in the study or had not completed their investigations History of Hyperthyroidism or hypothyroidism History of thyroid hormone therapy History of thyroid surgery Glasgow coma scale=3 & Glasgow coma scale=4 with fixed pupils
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICU length of stay. Timepoint: Since the time of trauma to discharge from the hospital. Method of measurement: Day. | — |
Secondary
| Measure | Time frame |
|---|---|
| Glasgow outcome scale extended. Timepoint: Three & six month after traumatic brain injury. Method of measurement: Glasgow outcome scale extended. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHosseinali Khalili
Shiraz University of Medical Sciences
Outcome results
None listed