effect of Propranolol in Traumatic Brain Injury (TBI)

Evaluation of the effect of Propranolol on the Prognosis of Traumatic Brain Injury (TBI)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130310012776N4

Enrollment

110

Registered

2018-08-02

Start date

2017-12-06

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TBI. Diffuse traumatic brain injury

Interventions

Intervention 1: Intervention group: 20 mg propranolol every 8 hours for 10 days. Intervention 2: control group: no drug use.

Eligibility

Sex/Gender

All

Age

16 Years to No maximum

Inclusion criteria

Inclusion criteria: age >18 years blunt brain injury mechanism admission to neurosurgical intensive care unit (NICU)

Exclusion criteria

Exclusion criteria: patients were prescribed regular beta-blocker therapy pre-admission those suffering any extracranial injuries requiring invasive interventions or surgery

Design outcomes

Primary

Measure	Time frame
Glasgow Outcome Score Extended (GOS-E). Timepoint: 6 months. Method of measurement: clinical exam.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosseinali Khalili

Shiraz University of Medical Sciences

khalili_h@sums.ac.ir+98 71 3624 8980

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026