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Trans Epithelial PRK for Treatment of High Astigmatic Error

Efficacy and Safety of Trans Epithelial Compared to Conventional Photorefractive Keratectomy for Treatment of Astigmatism of more than 3 Diopters.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130306012724N5
Enrollment
40
Registered
2021-01-27
Start date
2020-11-21
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Myopia. Condition 2: Astigmatism. Myopia, bilateral Unspecified astigmatism, bilateral

Interventions

Intervention 1: Intervention group: Trans-epithelial PRK for treatment of myopic astigmatism with SCHWIND AMARIS 1050RS (eye-tech-solutions, Kleinostheim, Germany) excimer laser system. Intervention 2

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Stable refraction during the last year No history of wearing contact lens for at least 3 weeks before the examination No history of Keratoconus and any type of corneal ectasia in the patient or his first-degree family sphere equal to or greater than -1 diopter and cylinder equal to or greater than 3 diopters in both eyes Satisfaction and full knowledge of patients to enter the plan

Exclusion criteria

Exclusion criteria: Previous ocular surgery Active eye disease, corneal dystrophy, retinal diseases, glaucoma, dry eye of any degree History of severe eye trauma Systemic diseases that potentially impair wound healing, including diabetes, collagen vascular disease, and pregnancy. Taking inhaled or systemic steroids actively or for 3 months before the procedure

Design outcomes

Primary

MeasureTime frame
Refractive astigmatism. Timepoint: Before, and 6 months after intervention. Method of measurement: Autorefractometry, combined with subjective refinement.

Secondary

MeasureTime frame
Visual acuity. Timepoint: Before, and 6 months after intervention. Method of measurement: Snellen chart.;Cornea slit-lamp examination. Timepoint: before, and 6 months after intervention. Method of measurement: Slit-lamp bio-microscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Babaei

Esfahan University of Medical Sciences

Leila8969@gmail.com+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026