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Efficacy of intramuscular ketamine injection compared to ketorolac in reducing acute postoperatve pain in Percutaneous Nephrolithotomy (PCNL) surgery.

Efficacy of intramuscular ketamine injection compared to ketorolac in reducing acute postoperatve pain in Percutaneous Nephrolithotomy (PCNL) surgery.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130304012695N21
Enrollment
120
Registered
2025-10-21
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain. po

Interventions

Intervention 1: Intervention group: After induction of anesthesia and intubation of the patients and taking the appropriate surgical position, 1 mg/kg of ketamine (Exir Pharmaceutical Company) is inje

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Ages 20-65 who have kidney stones Candidate for stone removal surgery using Percutaneous nephrolithotomy

Exclusion criteria

Exclusion criteria: Uncontrolled diabetes,pressure Uncontrolled hypertension Psychological disorders History of ketamine use Addiction to narcotic compounds

Design outcomes

Primary

MeasureTime frame
Acute Postoperative Pain. Timepoint: In recovery room and 1,6,12,18 and 24 hours after surgery. Method of measurement: Visual Analog Scale(VAS score).

Secondary

MeasureTime frame
The patient's level of alertness and drowsiness. Timepoint: 5, 10, and 20 minutes after extubation. Method of measurement: Sedition grading 1-5.;The first time need for analgesia after surgery. Timepoint: During 6 hours after surgery. Method of measurement: In terms of time in minutes, the first time an analgesic is injected after patients are extubated.;Total analgesics consumption during the first 24 hr after surgery. Timepoint: One time at the end of the first 24 hours after operation. Method of measurement: According to the patient file and nursing report.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Khajavi

Tehran University of Medical Sciences

khajavim@tums.ac.ir+98 21 6312 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026