Sedation for bronchoscopy.
Conditions
Interventions
Intervention 1: Intervention group: 10 ml of normal saline containing 1 mg/kg diphenhydramine (manufactured by Raha Pharma) is prepared with the help of an anesthetist according to the patient s group
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: All candidates for fiberoptic bronchoscopy aged 20-70 years who need sedation
Exclusion criteria
Exclusion criteria: Patients who have a history of drug addiction or are taking methadone Patients who take neurologic or psychoactive drugs Patients with a history of renal and liver failure History of allergy to diphenhydramine History of ischemic heart disease Patients with hemodynamic instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of sedation and agitation. Timepoint: At the beginning and 2, 5, 10 and 15 minutes of bronchoscopy. Method of measurement: Based on the criteria of the Richmond Agitation Sedation Scale.;Amount of propofol boluses in cases of insufficient sedation. Timepoint: Agitation degree greater than one during bronchoscopy. Method of measurement: At the end of bronchoscopy based on mg.;Hemodynamic indicators ,heart rate and blood pressure. Timepoint: Before drug induction and 5, 10 and 15 minutes after starting bronchoscopy and during recovery. Method of measurement: From patient monitoring.;Hypoxemia. Timepoint: During bronchoscopy. Method of measurement: By pulse oximetry.;Recovery time. Timepoint: From the end of bronchoscopy to the time of leaving the bronchoscopy department. Method of measurement: By the Chronometer based on minutes. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadreza Khajavi
Tehran University of Medical Sciences
Outcome results
None listed