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Effect of Tadalafil in treatment of Overactive bladder

Comparison of the efficacy of Tadalafil , Toltrodine and Placebo in reduction of symptoms severity of women with Urgency,frequency syndrom / Overactive bladder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013030212668N1
Enrollment
90
Registered
2013-05-21
Start date
2013-02-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overactive bladder syndrom. Bladder contracted

Interventions

Intervention 1: Control group: Tolterodine, Tab. 2 mg Oral, q12h for 4 weeks. Intervention 2: Intervention group: Tadalafil, Tab. 20 mg Oral, qod for 4 weeks. Intervention 3: Control group: Placebo(gl
Treatment - Drugs
Placebo
Control group: Tolterodine, Tab. 2 mg Oral, q12h for 4 weeks
Intervention group: Tadalafil, Tab. 20 mg Oral, qod for 4 weeks
Control group: Placebo(glucose), Tab. 1 Number Oral, qod for 4 weeks

Sponsors

Vice-Research of Medical School of Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Female with urgency with or without urge incontinence; First presentation of disease; Nonmenpause; Age range between 18 and 50 years old. Exclusion criteria: Previous medication therapy; Abnormal ultrasonography of kidneys,ureters and bladder; Positive urine cultur; Diabetes; Identified norologic disorders; Age less than 18 years old; Age greater than 50 years old; Menopause.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction of the symptoms severity. Timepoint: Before and 4 weeks after treatment. Method of measurement: ICIQ-OAB questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Sari motlagh

Tabriz University of Medical Sciences

motlagh.reza.dr@gmail.com+98 41 1334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026