knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group 1: Wishca, patients receiving WishCa herbal cream produced in IMD Company (Dr. Kamkar International Laboratory) contains the active ingredient of 7 herbs
Patients were asked to apply 1 mL of ointment 3 times a day, topically on the osteoarthritic knee. Intervention 2: Intervention group 2: Capsaicin, patients receiving Capex 0.034%, produced by Barijes
Patients were asked to apply 1 mL of ointment 3 times a day, topically on the osteoarthritic knee. Intervention 3: Control group: Diclofenac patents receiving Diclofenac Diethylammonium Salt Eq To dic
Patients were asked to apply 1 mL of ointment 3 times a day, topically on the osteoarthritic knee.
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: confirmed knee osteoarthritis according to American Rheumatology Association criteria history of knee pain ages 30 to 70 knee pain on most days of >40 mm on a 100 mm VAS on the worst knee giving informed consent
Exclusion criteria
Exclusion criteria: patient with other forms of arthritis (including secondary osteoarthritis, Rheumatic diseases a significant knee injury Having Low Back Pain and other referral pain to the knee History of arthroscopy in the previous 6 months, History of corticosteroid injection in the last 3 months History of knee surgery History of the knee clinical trials participation History of intra-articular injection of hyaluronic acid in the previoHistory of malignancyus 6 months open knee wound active dermatitis Infectious disease involving joints like TB or brucellosis acute psychological illness (especially depression) History of malignant neoplasm history of lower limb trauma leads to rupture of the meniscus, ligament, or capsule Patients with increased complaints and who are not satisfied with continuing medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms and function of affected knee. Timepoint: At the baseline, the end of week 1 and 4 with one week washout period. Method of measurement: KOOS questionnaire.;Pain. Timepoint: At the baseline, the end of week 1 and 4 with one week washout period. Method of measurement: VAS visual analogue scale.;Range of motion. Timepoint: At the baseline, the end of week 1 and 4 with one week washout period. Method of measurement: Angle measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Hosseinnezhad
Islamic Azad University
Outcome results
None listed