Comparison of Anesthesia Success Rate in Mandibular Inflammatory Tooth Between two Different Injection Techniques

Comparison of Success Rate of Inferior Alveolar Nerve Block versus IntraOsseous Injection For Pulpal Anesthesia in The Posterior Mandibular Teeth with Irreversible Pulpitis in patients attending to Afzal dental clinic, Isfahan, Iran 1391-92

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013022712634N1

Enrollment

Registered

2013-12-25

Start date

2012-10-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tooth with irreversible pulpitis. Pulpitis: NOS acute chronic (hyperplastic)(ulcerative) irreversible reversible

Interventions

Intervention 1: For the first group, primary pulpal anesthesia will provide with Intra Osseous injection of Mepivacaine 3%. Intervention 2: For the second group, primary pulpal anesthesia will provide

Treatment - Other

For the second group, primary pulpal anesthesia will provide with Inferior Alveolar Nerve Block injection of Mepivacaine 3%

For the first group, primary pulpal anesthesia will provide with Intra Osseous injection of Mepivacaine 3%

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) Patients with at least one posterior mandibular tooth with irreversible pulpitis for pulp therapy that each pulp therapy would be appliable thoroughly in one visit; 2) No history of taking any medication that would alter the inflammatory response of the pulp or provide analgesia for the previous 14 days; 3) No history of major systemic or cardiovascular disease; 4) Patients aged 18 to 65 years old; 5) Absence of acute inflammation and advanced periodontal disease at the injection area; 6) Provision written informed consent; Exclusion criteria: 1) Any history of alergy to anesthetic solutions; 2) lack of cooperation or interest of patient to continue the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Success of the Anesthesia. Timepoint: After the Injection and during root canal therapy (RCT). Method of measurement: Vitality pulp test (pulp tester and endo ice) before RCT and questioning from patients during RCT.;Pain. Timepoint: During injection of Anesthetic solution. Method of measurement: Heft-parker visual Analogue Scale.;Blood Pressure. Timepoint: Before and After Anesthetic injection. Method of measurement: Digital indicator -mmhg.;Onset of Anesthesia. Timepoint: After the injection with 1-minute intervals for a period of 15 minutes. Method of measurement: Vitality pulp test (pulp tester and endo ice).;Duration of Anesthesia. Timepoint: From the beginning to the end of RCT. Method of measurement: Asking from the patients.	—

Measure

Time frame

Success of the Anesthesia. Timepoint: After the Injection and during root canal therapy (RCT). Method of measurement: Vitality pulp test (pulp tester and endo ice) before RCT and questioning from patients during RCT.;Pain. Timepoint: During injection of Anesthetic solution. Method of measurement: Heft-parker visual Analogue Scale.;Blood Pressure. Timepoint: Before and After Anesthetic injection. Method of measurement: Digital indicator -mmhg.;Onset of Anesthesia. Timepoint: After the injection with 1-minute intervals for a period of 15 minutes. Method of measurement: Vitality pulp test (pulp tester and endo ice).;Duration of Anesthesia. Timepoint: From the beginning to the end of RCT. Method of measurement: Asking from the patients.

—

Secondary

Measure	Time frame
Hematoma. Timepoint: One hour after the injection. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShafeie Maryam

Isfahan University of Medical Sciences

marymahsash@gmail.com+98 31 1226 3421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 7, 2026