Benefits of Using Intrathecal Buprenorphine

Comparing the Analgesic Effects of Lidocaine Plus Buprenorphine and Lidocaine Alone In Women With Cesarean Section Under Spinal Anesthesia,Babol University of Medical Sciences

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013022112552N1

Enrollment

400

Registered

2013-06-07

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain managment and adverse effect of intratechal buprenorphine. Reactions and Intoxications From Maternal Opiates and Tranquillizers Administered During Labour and Delivery

Interventions

In the Case group, 65-70 mg (1.3 to 1.4 cc) of 5% Lidocaine Plus 0.2 cc of Bupernorphine Will be Infused. And in the Control Group, 65-70 mg (1.3-1.4 cc) of 5% Lidocaine Plus 0.2 cc of 0.9% Saline N

Treatment - Drugs

In the Case group, 65-70 mg (1.3 to 1.4 cc) of 5% Lidocaine Plus 0.2 cc of Bupernorphine Will be Infused. And in the Control Group, 65-70 mg (1.3-1.4 cc) of 5% Lidocaine Plus 0.2 cc of 0.9% Saline

Eligibility

Sex/Gender

Female

Age

17 Years to 41 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: All pregnant women candidate for elective cesarean section, in ASA class I (American Society of Anesthesiology) aged 17-41 Years. Exclusion Criteria: Maternal or fetal contraindication for spinal anesthesia; Severe fetus distress; Emergency Cesarean; Addiction, Drug or OTC abuse, Using Anti-epileptic drugs, Blood pressure more than 140/90 mmHg, Gestational diabetes,Psychiatric problems; Uncontrolled co-existent internal disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain free period after operation. Timepoint: Pain assessment before, during and after surgery with Visual Analogue Score (VAS). Method of measurement: Visual Analogue Scale (VAS).	—

Secondary

Measure	Time frame
Post Operative Nausea. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Questionnaire.;Post Operative Vomitting. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Questionnaire.;Hemodynamic Factors. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Standard Manometer, Standard Therometer.	—

Measure

Time frame

Post Operative Nausea. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Questionnaire.;Post Operative Vomitting. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Questionnaire.;Hemodynamic Factors. Timepoint: Before anesthesia, 5 Min interval after spinal anesthesia, then every 6 hours in the ward. Method of measurement: Standard Manometer, Standard Therometer.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Jabbari

Babol Univesity of Medical sciences, Golestan Univesity of Medical Sciences

amir_a_78@yahoo.com, anesth.jabbari@mubabol.ac.ir+98 11 1223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026