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Bupropion in the treatment of adult ADHD

Efficacy of bupropion for attention deficit hyperactivity disorder in adults: a double blind and placebo controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201302201556N51
Enrollment
40
Registered
2013-02-23
Start date
2013-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disturbance of activity and attention. Disturbance of activity and attention

Interventions

Placebo
Tablet Bupropion(150-300 mg/day) as intervention group for 6 weeks
Placebo for 6 weeks as control group
Intervention 1: Tablet Bupropion(150-300 mg/day) as intervention group for 6 weeks. Intervention 2: Placebo for 6 weeks as control group.
Treatment - Drugs

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Diagnosis of ADHD based on DSM-IV ; age between 20-60 Exclusion Criteria:Chronic medical disease including seizure,cardiovascular disease, CVA and organic brain disease;substance abuse or dependence during past six months;nursing or pregnant patients; history of tic disorder; receiving of any psychotropics drugs during past two weeks, mental retardation ; history of suicide attempt, psychosis or aggressiveness; receiving psychotropic drugs; receiving psycho-stimulants or atomoxetine during past three months; bipolar disorder

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of ADHD. Timepoint: Week 0 (before treatment) and Weeks 3 and 6 after treatment. Method of measurement: by Adult ADHD Self-Report Scale and Conners Adult ADHD Rating Scales–Self-Report-screening version.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactProf. Shahin Akhondzadeh

Tehran University of Medical Sciences

S.akhond@sina.tums.ac.ir+98 21 5541 2222

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026