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Effects of intracuff dexamethasone, intravenous dexamethasone & application of bethametasone ointment on endotracheal tube cuff on Post-intubation sore throat

Effects of intracuff dexamethasone, intravenous dexamethasone & application of bethametasone ointment on endotracheal tube cuff on Post-intubation sore throat

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201302178531N2
Enrollment
120
Registered
2013-03-07
Start date
2009-08-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prevention of sore throat after tracheal intubation. Anaesthesiology devices associated with adverse incidents

Interventions

Intervention 1: First group: Intracuff application of 16 mg dexamethasone. Intervention 2: Third group: application of bethametasone ointment on endotracheal tube cuff. Intervention 3: Second group: I
Prevention
First group: Intracuff application of 16 mg dexamethasone.
Third group: application of bethametasone ointment on endotracheal tube cuff.
Second group: Intravenous application of 8 mg dexamethasone.
Fourth group or control group: filling the endotracheal tube cuff with air.

Sponsors

Ladan Ansari
Lead Sponsor
Islamic Azad University, Tehran Medical Branch, Vice chansellor for research
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 60>age>18 yr; ASA class 1 or 2; no URI infection or sorethroat at the time of surgery; no possibility of difficult air way; no candidate of surgery on air way; candidate of general anesthesia & tracheal intubation; no contraindication for receiving steroids. Exclusion criteria: intraoperation pharyngeal packing; intraoperation NG tube placement.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sore throat after tracheal intubation. Timepoint: After recovery period, 8 & 24 hours after intervention. Method of measurement: Questionaire & VAS method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLadan Ansari

Tehran Medical Branch of Islamic Azad University

Ladanansari46@gmail.com+98 21 8876 4030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026