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The effect of ketamine in prevention of pain from propofol injection

The effect of ketamine in preventing propofol injection pain in patients who taking general anesthesia with propofol induction- A ranomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201302177093N4
Enrollment
168
Registered
2013-12-22
Start date
2012-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

propofol injection pain. Parenteral anaesthetics

Interventions

Intervention 1: received ketamine 0.1 mg/kg while a tourniquet had been applied 10 cm above the injection site and after 30 seconds tourniquet was released and propofol injected through a vein on the
Treatment - Drugs
received ketamine 0.1 mg/kg while a tourniquet had been applied 10 cm above the injection site and after 30 seconds tourniquet was released and propofol injected through a vein on the dorsum of the ha
0.1 mg/kg ketamine administered without tourniquet application after 30 seconds propofol injected through a vein on the forearm.
0.1 mg/kg ketamine administered without tourniquet application after 30 seconds propofol injected through a vein on the dorsum of the hand.
propofol injected without pre injection of ketamine through a vein on the forearm.
propofol injected without pre injection of ketamine through a vein on the dorsum of the hand.

Sponsors

North Khorasan University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria:ASA Class 1,2;Candidate Of General Anesthesia With Propofol Injection Exclusion Criteria : Epilepsy;Known Cardiovascular Disease; Known Neurological Disease;GCS<15;Sensitivity History;Opioid And Sedative Drug As Premedication

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Propofol injection pain. Timepoint: During Drug Injection. Method of measurement: Verbal Response Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sabermoghadam

North Khorasan University of Medical Sciences, Bojnurd, Iran

sabermoghadam41@gmail.com+98 58 4229 6965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026