chronic Post-traumatic stress disorder( PTSD). Post-traumatic stress disorder
Conditions
Interventions
Intervention 1: The case group received SSRI( Serteraline 50-200 mg or citalopram 20-40 mg) daily for 6 weeks. received Pregabalin (75 mg/day for the first week then 75 mg twice daily for the second w
Treatment - Drugs
The case group received SSRI( Serteraline 50-200 mg or citalopram 20-40 mg) daily for 6 weeks. received Pregabalin (75 mg/day for the first week then 75 mg twice daily for the second week and continue
control group received placebo and routine treatment daily for 6 weeks.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: diagnose with PTSD based on DSM-IV-TR criteria, age between 30 and 65 years, had no significant cognitive disorder and no history of drug abuse except for nicotine. Exclusion criteria: were unwillingness of patients to continue the trial; active medical disease, other diseases in axis one or two except for PTSD and sensitivity to Pregabalin.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post traumatic stress disorder. Timepoint: 0, 2, 4 and 6th weeks. Method of measurement: PCL test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: 0, 2, 4 and 6th weeks. Method of measurement: Spitzer Quality of Life index( SQL).;Depression. Timepoint: 0, 2, 4 and 6th weeks. Method of measurement: Hamilton Depression Rating Scale.;Anxiety. Timepoint: 0, 2, 4 and 6th weeks. Method of measurement: Hamilton Anxiety Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mahdi Baniasadi
Mashhad University of Medical Sciences
Outcome results
None listed