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Investigating the effect of peppermint essential oil on Gastric Residual Volume

Investigation of the Effect of Peppermint Essential Oil on Gastric Residual Volume in Mechanically Ventilated Patients Admitted to the Intensive Care

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130211012438N36
Enrollment
46
Registered
2025-05-29
Start date
2024-11-10
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated patients hospitalized in ICU. Dependence on respirator [ventilator] status

Interventions

Intervention 1: Intervention group: We dissolve 20 drops of 3% peppermint essence solution in 10 cc of water and gavage the patient three times a day (6 am, 2 pm, 9 pm) before meals for four days. Pep

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patient must be between 18 and 65 years old. Informed consent should be obtained from the patient's guardian. The patient should be under mechanical ventilation. At least 24 hours must have passed since the patient's presence in the ICU.

Exclusion criteria

Exclusion criteria: Diagnosis of gallbladder stones History of active gastrointestinal bleeding Diagnosis of malignancy Diagnosis of gastrointestinal ulcer Diagnosis of diabetes mellitus Diagnosis of pancreatitis Pregnancy and lactation Reported history of hypothyroidism according to the patient's companion Oral feeding or use of a duodenal feeding tube

Design outcomes

Primary

MeasureTime frame
Gastric Residual Volume in Mechanically Ventilated Patients. Timepoint: before the intervention and then 3 times a day at 6 am, 2 pm and 9 pm for 4 days. Method of measurement: 60 cc syringe.

Secondary

MeasureTime frame
Energy intake of patients under mechanical ventilation. Timepoint: Before the intervention and during the study 3 times a day at 6 am, 2 pm and 9 pm for 4 days. Method of measurement: The volume of received gavage.;C-reactive protein to investigate inflammation. Timepoint: Before the intervention and the end of the intervention. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Taghizadeh

Kashan University of Medical Sciences

taghizadeh_m@kaums.ac.ir+98 31 5500 9999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026