Chronic Obsructive Pulmonary Disease. chronic: bronchitis: asthmatic (obstructive) emphysematous with: airways obstruction emphysema obstructive: asthma bronchitis tracheob
Conditions
Interventions
Pearl Vitamin D 3 ,50,000 IU orally, weekly for 6 weeks.
Treatment - Drugs
Pearl Vitamin D 3 ,50,000 IU orally, weekly for 6 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 84 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Outpatients with COPD and Vitamin D deficiency or insufficiency Exclusion criteria:Chronic renal failure,Urolithiasis,Parathyroid disease,Peripheral vascular disease,Inability to walk because of neuromuscular or advanced degenerative joint disease;Pulmonary artery pressure more than 50 mmHg,Left ventricular ejection fraction less than 40% ,admission for COPD exacerbation within previous 2 weeks
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The maximum distance that patients walk during 6 minute walk test. Timepoint: At the initiation of the study and 3 months after vitamin D replacement. Method of measurement: There is a specialised corridor in department of pulmonary medicine where the distance passed by the patient can be measured on meter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Percieved dyspnea during 6 minute walk test. Timepoint: At the initiation of study and three months after vitamin D replacement. Method of measurement: Visual analogue scale.;Forced expiratory voulme in 1st second. Timepoint: at the initiation and three moths after vitamin D replacement. Method of measurement: Spirometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrnaz Asadi Gharabaghi
Tehran University of Medical Sciences
Outcome results
None listed