CNS diseases. Other disorders of the nervous system
Conditions
Interventions
Intervention 1: combination of 40 mg/kg of chloral hydrate and 1mg/kg hydroxyzine. Intervention 2: 40 mg/kg of chloral hydrate and 0.5mg/kg oral midazolam.
combination of 40 mg/kg of chloral hydrate and 1mg/kg hydroxyzine
40 mg/kg of chloral hydrate and 0.5mg/kg oral midazolam
Sponsors
Deputy of Research of Shahid Sadoughi University of Medical Sciences,Yazd,Iran
Eligibility
Sex/Gender
All
Age
1 Years to 7 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Children who are referred to MRI Unit but don’t obey, 2. Age 1-7 years old 3. Class 1 or 2 of ASA 4. Do not receive a sedative hypnotic agent within the past 48 hours Exclusion criteria: 1. Presence of gastritis or any other serious systemic diseases 2. Severe systemic reaction 3. History of allergy to drug 4. The patient does not use the drug completely
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adequate sedation (Ramsay score of four is attained). Timepoint: every 15 minutes. Method of measurement: clinical exam.;Success in taking of MRI. Timepoint: every 15 minutes. Method of measurement: clinical exam. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to induction of adequate sedation. Timepoint: every 15 minutes. Method of measurement: clinical examination.;Side effects. Timepoint: every 15 minutes. Method of measurement: clinical examination.;Total stay time in MRI unit. Timepoint: Every 30 minutes. Method of measurement: asking from parents.;Caregiver’s satisfaction. Timepoint: after two hours of drug use. Method of measurement: asking from caregiver. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Razieh Fallah
Shahid Sadoughi University of Medical Sciences , Yazd , Iran
Outcome results
None listed