Effect of ginger and chamomile on nausea and vomiting caused by chemotherapy Comparing the effect of ginger and chamomile on nausea and vomiting caused by chemotherapy

Comparing the effect of ginger and chamomile on nausea and vomiting caused by chemotherapy in women with breast cancer referred to the Breast cancer research centre, jahad daneshgahi in 2013

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013020912404N1

Enrollment

Registered

2015-03-14

Start date

2013-05-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer. Malignant Neoplasm of Breast

Interventions

Intervention 1: Intervention group 1 hour for 5 days before and 5 days after chemotherapy, 2 times a day and 500 mg capsules of powdered ginger root in addition to routine antiemetic regimen consistin

Treatment - Drugs

Intervention group 1 hour for 5 days before and 5 days after chemotherapy, 2 times a day and 500 mg capsules of powdered ginger root in addition to routine antiemetic regimen consisting of dexamethaso

Intervention group 1 hour for 5 days before and 5 days after chemotherapy, 2 times a day and 500 mg capsules of Matricaria Chamomilla extract in addition to routine antiemetic regimen consisting of d

Control group, routine antiemetic regimen consisting of dexamethasone and metoclopramide and Aprepitant capsule was consumed

Eligibility

Sex/Gender

Female

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Presence of with breast cancer definite diagnosis by a pathologist? age between 20 and 60 years? receiving chemotherapy? ?having at least one ?chemotherapy session before? having history of nausea and vomiting after chemotherapy? having ?one-day chemotherapy sessions Exclusion criteria: multi-days chemotherapy sessions? simultaneous radiotherapy inducing ?nausea and vomiting such as whole body or upper abdomen RT? consuming warfarin and heparin for ?treatment? consuming ASA more than ??80?mg? receiving heparin (except for iv-lines)? history of ?blood discrasies? history of severe thrombocytopenia? allergy to ginger and chamomile or consuming during the ?past week? gastro-intestinal cancers? having other nausea and vomiting inducing factors except ?chemotherapy such as CNS tumors? HTN? renal failure or hepatic disorders? gastrointestinal ?problems like gastric or peptic ulcers? forgetting the use of capsules ??3 ?consecutive times or more

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea severity. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: A 10 centimeter visual analogue scale (VAS).;Number of Nausea episodes. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: Questionnaire.;Number of Vomiting episodes. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: Questionnaire.	—

Measure

Time frame

Nausea severity. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: A 10 centimeter visual analogue scale (VAS).;Number of Nausea episodes. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: Questionnaire.;Number of Vomiting episodes. Timepoint: For five days (from one hour before until five days after chemotherapy). Method of measurement: Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Zahra Kashaninia

Welfare and Rehabilitation Sciences University of Medical Sciences

kashaninia@uswr.ac.ir+98 21 2218 0036

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026