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The effect of endometrial local injury in increasing pregnancy rate

Evaluating the effect of endometrial local injury in increasing pregnancy rate in patients undergoing ART (IVF/ICSI)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201302091141N13
Enrollment
220
Registered
2013-03-07
Start date
2013-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Pipelle endometrial sampling 19-21th day in the cycle prior to IVF transfer cycle..
Treatment - Surgery
Pipelle endometrial sampling 19-21th day in the cycle prior to IVF transfer cycle.

Sponsors

Royan Institute
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Previous failed In-vitro fertilization embryo transfer cycle (at least =1 cycles have failed); Patients who are good responders and have good quality embryos in the previous attempts; Age of patients up to 40 years. Exclusion Criteria: Those with intramural fibroid distorting the endometrial cavity/sub-mucous myoma; Those with sonographically detected hydrosalpinx; age over than 40 years old; poor responders to ovarian stimulation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: 4-6 weeks after embryo transfer. Method of measurement: Ultrasound visualization of a gestational sac.

Secondary

MeasureTime frame
Biochemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: BhCG test.;Implantation. Timepoint: 4-6 weeks after embryo transfer. Method of measurement: Number of sacs by Sonography.;Endometrial thickness. Timepoint: Third day. Method of measurement: Sonography.;Early abortion. Timepoint: Week 12. Method of measurement: Sonography.;Late abortion. Timepoint: Week 20. Method of measurement: Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mahnaz Ashrafi

Royan Institute

Ashrafim@royaninstitute.org+98 21 2356 2644

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026