Treatment of intrabony defects

Comparison of Enamel Matrix Derivatives (EMD) to EMD/Decalcified Freezed Dried Bone Allograft (DFDBA) in the Treatment of Human Intrabony Periodontal Defects: A Controlled Clinical Trial With 6 Month Re-entry

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013020710501N2

Enrollment

Registered

2013-03-22

Start date

2007-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontal disease. Chronic periodontitis

Interventions

Intervention 1: Using EMD alone in the treatment of intrabony defects (control group). Intervention 2: Using EMD /DFDBA in the treatment of intrabony defects (Test group).

Treatment - Surgery

Using EMD alone in the treatment of intrabony defects (control group)

Using EMD /DFDBA in the treatment of intrabony defects (Test group)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criteria were the presence of paired interproximal 2 or 3 wall vertical defects =3mm deep (distance between alveolar crest and base of the defect in intraoral periapical radiography) along with an interproximal probing depths =5.0 mm following initial non-surgical therapy. The patient exclusion criteria consisted of : 1) known systemic diseases and/or drug therapy known to interfere with wound healing; 2) compromised immune system; 3) pregnancy and\ or lactation; 4) cigarette smoking; 5) using systemic antibiotics or having received antibiotic therapy in the last 3 months; and 6) O´Leary plaque score>20%.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bony defect fill. Timepoint: Baseline and 6 month later. Method of measurement: periodontal probe.;Bony defect fill. Timepoint: Baseline and 6 month later. Method of measurement: periodontal probe.	—

Secondary

Measure	Time frame
Clinical Attachment level. Timepoint: baseline and 6 month later. Method of measurement: periodontal probe.;Gingival recession. Timepoint: baseline and 6 month later. Method of measurement: periodontal probe.;Clinical probing depth. Timepoint: baseline and 6 month later. Method of measurement: periodontal probe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNader Abolfazli

Dental faculty, Tabriz University of medice sciences

abolfazli@tbzmed.ac.ir+98 41 1335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026