Indirect hyperbilirubinemia in neonate. Physiological jaundice (intense)(prolonged) NOS
Conditions
Interventions
Intervention 1: First group was given ursodeoxycholic acid 10-15 mg/kg divided q12h before starting phototherapy till exclusion from study. In the first day, laboratory tests included estimation of to
Treatment - Drugs
First group was given ursodeoxycholic acid 10-15 mg/kg divided q12h before starting phototherapy till exclusion from study. In the first day, laboratory tests included estimation of total bilirubin (d
Second group that is control group received no medications and only underwent phototherapy.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 28 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: birth-weight 2500-4000 gr; gestational age between 38-41 weeks; breastfeeding neonate; total bilirubin 14-20 mg/dl and neonates age older than three days. Exclusion criteria: infants with incompatible ABO, Rh; G6PD deficiency; direct hyper billirubinemia; septicemia or diseases that are implicated in causing jaundice; premature infants; infants of diabetic mothers.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of need phototherapy. Timepoint: Since start study till finish study. Method of measurement: Timer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum total bilirubin. Timepoint: Since start study &12, 24, 36, 48 hour. Method of measurement: Blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGhashghaei Saadi Elham MD
Shiraz University of Medical Sciences
Outcome results
None listed