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The effect of Nitrous Oxide in comparison to Oxygen combined with Fentanyl on the staying time and pain reduction in renal colic patients at Emergency room

The effect of Nitrous Oxide in comparison to Oxygen combined with Fentanyl on the staying time and pain reduction in renal colic patients at Emergency room

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013020512369N1
Enrollment
120
Registered
2016-06-19
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal colic. Unspecified renal colic

Interventions

Intervention 1: At the beginning 50 microgram (µg) fentanyl was infused for all of the patients. First group was received mask of oxygen. Patients were able to remove the mask if their pain was relie
Treatment - Drugs
At the beginning 50 microgram (µg) fentanyl was infused for all of the patients. First group was received mask of oxygen. Patients were able to remove the mask if their pain was relief. If the pain

Sponsors

Vice chancellor for research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria were as follows: Age>18 yr; Definite diagnosis of renal colic; Stable hemodynamic (PR=60-100? SBP>100? SPO2>90%?RR=8-22); lack of analgesics usage during last 24 hour; absence of these conditions in patients history: asthma, COPD, intestinal obstruction, hypertension, heart failure, history of previous surgery on kidney and urinary tract, peptic ulcer, GI bleeding, previous history of allergy to fentanyl or other analgesic agents, loss of consciousness, head or chest trauma, pneumocephalus, pneumothorax, drug abuse, abdominal tenderness, rebound tenderness or guarding, retard menstruation; Fill the Informed consent form Patients were excluded if: The patient hemodynamic becomes unstable during the process of hospitalization; Hypersensitivity reaction to analgesic drugs occurred; The diagnosis were changed during the further investigations

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Duration of hospitalization. Timepoint: at the end of the intervention. Method of measurement: minutes by timer.;Severity of pain. Timepoint: before and 3-, 5-, 10- and 30-minute after the intervention. Method of measurement: visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOmid Ahmadi

Department of Emergency Medicine, Isfahan University of Medical Sciences

omid.ep@med.mui.ac.ir+98 31 3261 3464

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026