Cow milk protein allergy. Malabsorption due to intolerance to: carbohydrate-fat-protein-starch
Conditions
Interventions
Intervention 1: The control group received placebo without probiotics which are match for size, shape, and volume of contents and manufactured by the same company, daily for 4 weeks. Intervention 2: T
Placebo
Treatment - Drugs
The control group received placebo without probiotics which are match for size, shape, and volume of contents and manufactured by the same company, daily for 4 weeks
The study group will receive a synbiotic containing 1 billion Colony Forming Units (CFU) of ProtexinR Restore: a mixture of Lactobacillus casei, Lactobacillus rhamnosus, Streptococcus thermophilus, B
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1-12 months-old infants with the clinical symptoms of cow's milk protein allergy including rectal bleeding, diarrhea, vomiting and evidences of colitis; a good general condition, breast milk feeding and cow's milk consuming mother. The infants are excluded from the study if they had a known immune deficiency, gastro intestinal disease, positive stool culture, coagulopathy or are receiving any type of antibiotic therapy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of gastrointestinal symptoms. Timepoint: At the beginning of the study, 3 months after intervention. Method of measurement: The number of vomiting, colic, rectal bleeding and diarrhea. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the beginning of the study, 3 months after intervention. Method of measurement: Gram.;Head circumference. Timepoint: At the beginning of the study, 3 months after intervention. Method of measurement: centimeter.;Body length. Timepoint: At the beginning of the study, 3 months after intervention. Method of measurement: centimeter. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed