palpitations. Awareness of heart beat
Conditions
Interventions
Intervention 1: Placebo group: Hard gelatin capsule containing 500mg of Melissa leaf dry extract,twise a day,for 14 days. Intervention 2: drug groupe: Hard gelatin capsules containing 500 mg of bread
twise a day for 14 days.
Treatment - Drugs
Placebo
Placebo group: Hard gelatin capsule containing 500mg of Melissa leaf dry extract,twise a day,for 14 days
drug groupe: Hard gelatin capsules containing 500 mg of bread powder
twise a day for 14 days
Sponsors
School of Traditional Pharmacy,Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: palpitations (abnormal awareness of heartbeat) as one of the main presenting complaint; history of palpitation for at least three months; age between 18 and 60 years; informed consent. Exclusion criteria: mental retardation; psychosis and other serious psychological diseases confirmed by a psychologist; organic heart diseases confirmed by a cardiologist; serious chronic diseases; pregnancy; lactation; consumption of beta-blockers; consumption of antidepressants and anxiolytics and sedatives 10 days before the start of the study; declination of participation; irregular use of prescribed drugs; unpredicted side effects.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of palpitations' episodes. Timepoint: Before and after intervention. Method of measurement: asking patients to write it in the form.;Mean intensity of palpitations' episodes. Timepoint: Before and after intervention. Method of measurement: asking patients to estimate it by VAS and write down in the form. | — |
Secondary
| Measure | Time frame |
|---|---|
| Probable mental disorders. Timepoint: Before and after intervention. Method of measurement: validated General Health Questionnaire-28.;Drug side effects. Timepoint: Before and after intervention. Method of measurement: asking the patients to write their symptoms in the form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Alijaniha
School of Pharmacy, Shahid Beheshti University of Medical Sciences
Outcome results
None listed