Type 2 diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group will receive daily 3 cups of Chamomile tea immediately after the meal for 8 weeks( each cup of Chamomile tea is produced by putting Chamomile tea bag contains 3 gra
Treatment - Drugs
Intervention group will receive daily 3 cups of Chamomile tea immediately after the meal for 8 weeks( each cup of Chamomile tea is produced by putting Chamomile tea bag contains 3 grams in 150 cc of
control group 3 cups lukewarm boiled water daily over the same period (per cup after meal consumption)
Sponsors
Nutritional Research Center of Tabriz University of Medical Sciences
Vice chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Type 2 diabetes for at least 6 months, age between 30-60 years, usage of blood glucose lowering drugs Exclusion criteria: usage of nutritional supplements in the past 3 months or during the study, usage of insulin, Pregnancy or lactation, BMI more than 37, Renal failure, liver disease, Cardiovascular disease, thyroid disorders, History of allergy, smoking, alcohol usage, Following a specific diet, Taking corticosteroids or immunosuppressive drugs
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: Enzymatic colorimetric.;Fasting insulin serum. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: ELISA assay.;HbA1C (Glycosilated hemoglobin). Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: ELISA.;Insulin resistance. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: HOMA-IR calculation.;Lipid profiles (TC, TG, LDL-C, HDL-C). Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: Enzymatic methods for TC,TG and HDL-C For LDL-C : Freidwald’s formula: LDL-C = TC- HDL-C - (TG/5).;Serum malondialdehyde(MDA). Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: spectrophotometry.;Serum total antioxidant capacity. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: spectrophotometry.;GPX activity. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: spectrophotometry.;SOD activity. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: spectrophotometry.;Catalase enzyme activity. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: spectrophotometry.;Hc-CRP. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: immunoturbidimetry.;TNF-a. Timepoint: Baseline and after 8 weeks of intervention. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Macronutrients intake. Timepoint: before and after 8 weeks intervention. Method of measurement: 24-h recall Questionnaire.;Anthropometric index(weight and Body Mass Index). Timepoint: before and after 8 weeks intervention. Method of measurement: Analogue scale for weight and weight(Kg)/Square Height for body mass index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Zemestani
Tabriz University of Medical Sciences
Outcome results
None listed