Effect of Paracetamol on Postop Pain

Comparison the effect of Paracetamol and Morphine with IV-PCA in control of postop pain in Cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013012712298N1

Enrollment

Registered

2013-05-19

Start date

2010-08-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystectomy. Acquired absence of other parts of digestive tract

Interventions

Intervention 1: Paracetamol. Controlling pain after laparotomy surgery (Cholecystectomy). with maximum dose 125 mg per hour with intravenous PCA. Lasting 8 hours after surgery. Intervention 2: Morphin

Treatment - Drugs

Paracetamol. Controlling pain after laparotomy surgery (Cholecystectomy). with maximum dose 125 mg per hour with intravenous PCA. Lasting 8 hours after surgery

Morphine. Controlling pain after laparotomy surgery (cholecystectomy). with maximum dose 20.0 mg per kg in hour with intravenous PCA. Lasting 8 hours after surgery

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :patients with ASA 1 and 2 ; 15 to 65 years ; who were undergoing Cholecystectomy Operation ; takes less than2.5 hours.Exclusion criteria : People using opioids, painkillers and sedatives regularly and in large doses ; patients with a history of lung problems ;patients with a history of liver problems

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post Operative Pain. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: VAS.	—

Secondary

Measure	Time frame
Nausea. Timepoint: 2, 4, 6 And 8 Hours After Intervention. Method of measurement: VAS.;Satisfaction. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: VAS.;Pruritus. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Yes or no.;Arterial Oxygen Desaturation. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Yes or no.;Changes in Blood Pressure. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Into three groups: Low, Medium and High.;Changes in Heart rate. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Into three groups: low, medium and high.	—

Measure

Time frame

Nausea. Timepoint: 2, 4, 6 And 8 Hours After Intervention. Method of measurement: VAS.;Satisfaction. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: VAS.;Pruritus. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Yes or no.;Arterial Oxygen Desaturation. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Yes or no.;Changes in Blood Pressure. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Into three groups: Low, Medium and High.;Changes in Heart rate. Timepoint: 2, 4, 6 and 8 Hours after Intervention. Method of measurement: Into three groups: low, medium and high.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Pourfallah

Qazvin University of Medical Sciences

rpoorfallah@qums.ac.ir+98 26 3272 0831

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026