Postoperative Pain. Acute Pain
Conditions
Interventions
Intervention 1: After induction Paracetamol 1 gram in 100 milligrams normal saline in 15 minutes. Intervention 2: After induction 0.1 milligram per kilogram up to 8 milligrams Dexamethasone IV in 10 m
Treatment - Drugs
Placebo
After induction Paracetamol 1 gram in 100 milligrams normal saline in 15 minutes
After induction 0.1 milligram per kilogram up to 8 milligrams Dexamethasone IV in 10 milliliter normal saline in 15 minutes
After induction 100 milliliter normal saline in 15 minutes
Sponsors
Vice chancellor for research of Ahvaz Jondishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with ASA 1 or 2 ; the patients without history of any hepatic and renal disorder; without sensitivity to Paracetamol and Corticosteroids; without history of peptic ulcer disease; without history of treatment with Corticosteroids or other immunosuppressive drugs; without history of DM I and II; no drug abuse Exclusion criteria: patients with perioperative hemodynamic instability ; perioperative respiratory distress; perioperative nausea and vomiting or any important adverse effects .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: 0 (after extubation), 2, 6, 12 and 24 hours after surgery. Method of measurement: Visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse effects. Timepoint: In 24 hours after surgery. Method of measurement: Asking from patients.;Meperidine consumption. Timepoint: In 24 hours after surgery. Method of measurement: milligramms. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmin Mehrakizadeh
Ahvaz Jondishapour University of Medical Sciences
Outcome results
None listed