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The effect of Artichoke on fatty liver indices

The effect of Cynara scolymus L.on fatty liver indices

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130126012278N3
Enrollment
100
Registered
2018-02-21
Start date
2017-12-06
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non alcoholic Fatty Liver. Fatty (change of) liver, not elsewhere classified

Interventions

Chopped leaves of dried Artichoke- it is used twice a day (fasting in the morning and at night before bedtime) for 45 days. Brewing a tablespoon of leaf with a boiling cup (like tea) for 20 minutes on

Sponsors

Vice Chancellor for Research, Hamedan University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 30-65 years old Detection of Non-alcoholic Fatty Liver based on high levels of ALT and AST enzymes Ultrasound diagnosis of Fatty Liver BMI was more than 25 People who did not Use Antioxidant complementary during a month before sampling People who had not underlying diseases like heart acute disease, kidney, infections, diabetes, hepatitis B or C and other diseases of the liver Not having a severe weight losing or gaining regimens within 3 months before sampling Not using of effective drugs on weight during 3 months prior to sampling Not using drugs that are likely to be related to this disease (methotrexate, amiodarone, tamoxifen, corticosteroids, valproic acid)

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Alcohol drinking other liver diseases Diet or treatment for fatty liver in the last 3 months Autoimmune diseases and cancer Reluctance to continue research

Design outcomes

Primary

MeasureTime frame
Liver enzymes. Timepoint: At the beginning of study, 48 hours after the end of the study (this study will take 7 weeks). Method of measurement: blood assay results (including AST and ALT).

Secondary

MeasureTime frame
The amount of liver fat accumulation. Timepoint: 45 days. Method of measurement: Doppler color ultrasound.;Liver Enzymes. Timepoint: 45 days. Method of measurement: Blood examination Results.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Rajabi

Hamedan Agricultural and Natural Resources Research and Education Center

m.rajabi@iauh.ac.ir+98 81 3437 3587

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026