Chronic Renal Failure -Hemodialysis. Chronic Renal Failure -Dialysis
Conditions
Interventions
Intervention 1: For all patients in the intervention group,administered tablet clopidogrel 75 mg daily, orally for 6 months and patients were followed during this 6 months and monitored of graft th
Prevention
Placebo
For all patients in the intervention group,administered tablet clopidogrel 75 mg daily, orally for 6 months and patients were followed during this 6 months and monitored of graft thrombosis .
For all patients in the control grouop administered a tablet exactly similar to the clopidogrel and is made with starch composition,orally for 6 months, and patients were followed during this 6 mon
Sponsors
Kermanshah Univesity of Medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criterion: patients with end-stage renal failure who need to vascular access graft placement in upper extremity for hemodialysis. Exclusion criteria: pationts with advanced malignancies and hyper coagolation states; pationts with a history of venous access thrombosis; thrombocytopenia (450000/ml); erythrocytosis (hematocrite>55%); patients who receiving warfarin, aspirin or other salicylates, dipyridamole,sulfinpyrazone and ticlopidine or other conditions that anti platelet drugs are contraindicated.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thrombosis. Timepoint: Monthly for 6months. Method of measurement: Dupler Sonography and clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahman Alinezhad
Kermanshah Univesity of Medical sciences
Outcome results
None listed