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Effect of Mellis officinalis on serum oxidative stress and second degree wound healing

Effect of oral Mellis officinalis on serum oxidative stress and second degree wound healing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013012312246N1
Enrollment
60
Registered
2013-02-24
Start date
2012-12-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Second-degree burn. Burns of multiple regions, no more than second-degree burns mentioned

Interventions

Intervention 1: An infusion of lemon balm herb in the intervention group, 1.5 grams 1.5 grams 9 am to 9 pm Duration of intervention: 14 days. 5 ml venous blood (blood samples routinely taken from pati
Treatment - Drugs
An infusion of lemon balm herb in the intervention group, 1.5 grams 1.5 grams 9 am to 9 pm Duration of intervention: 14 days. 5 ml venous blood (blood samples routinely taken from patients) in the fir
No intervention is used in control groupe . A venous blood sample (5 ml) on the first and fifteenth day of the study is to measure serum antioxidant levels occurs., A second-degree burn wound in the f

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having burn between 15 to 50 percent of body surface; having age range from 18 to 15 years old; hospitalization in burn unit; non-fasting; not having underlying diseases such as thyroid disorders, diabetics, cancer or infectious diseases; no records of drugs abuse (alcohol, narcotic drugs, under treatment with sedatives and anti-depressants); volunteered to participate in the survey; not pregnant; no records of taking supplementary antioxidants and the burn is not caused by electricity (electric devices). Exclusion criteria: refraining from continuing participation in the study; possible allergy to lemon balm; patient’s discharge; transfer to another center and death of the patient.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Burned Wound pain. Timepoint: Baseline - the seventh day - the fifteenth day. Method of measurement: Numerical scale of 0-10.

Primary

MeasureTime frame
Burning wound healing. Timepoint: Baseline - the seventh day - the fifteenth day of the intervention. Method of measurement: bates-jensenWound assessment tool.;Serum antioxidant levels. Timepoint: Baseline (pre-intervention) and the end of the intervention (the fifteenth day. Method of measurement: Tests measuring levels of serum antioxidants.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasumeh Abbasdust Aarbastan

Arak University of Medical Sciences

m.abbasdost@arakmu.ac.ir; m.abasdust@yahoo.com+98 21 8840 3119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026