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Comparing the effects of Tranexamic acid and Mefenamic acid in treating heavy menstrual bleeding

Comparing the effects of Tranexamic acid and Mefenamic acid in treating menorrhagia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013011912190N1
Enrollment
60
Registered
2013-02-23
Start date
2011-02-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menorrhagia. Noninflammatory disorders of female genital tract

Interventions

Intervention 1: Intervention group:Tranexamic acid capsule 250 mg ,oral, every 8 hour in the first 3 days of bleeding on two subsequent cycles. Intervention 2: Control group:Mefenamic acid capsule 250
Treatment - Drugs
Intervention group:Tranexamic acid capsule 250 mg ,oral, every 8 hour in the first 3 days of bleeding on two subsequent cycles
Control group:Mefenamic acid capsule 250 mg ,oral,every 8 hour in the first 3 days of bleeding on two subsequent cycles

Sponsors

Taleghani Hospital of Tehran
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women aged 15-49 suffering from heavy menstrual bleeding or long menstrual duration. Exclusion criteria: organic causes were excluded by history, physical exam, lab test.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Menstrual duration. Timepoint: one month before treatment,two subsequent month during treatment and one month following treatment. Method of measurement: questionnaire.;Menstrual bleeding volume. Timepoint: one month before treatment,two subsequent month during treatment and one month following treatment. Method of measurement: Pictorial chart on which patients marked the type and the number of pads theyused during menstrual bleeding.

Secondary

MeasureTime frame
Complication ,like vertigo, dyspepsia,epigasteric pain,thrombosis. Timepoint: one month following treatment. Method of measurement: questionnaire.;Choosing the drug if the problem recur. Timepoint: one month following treatment. Method of measurement: questionnaire.;Patient satisfaction with the treatment. Timepoint: one month following treatment. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShiva Hadadian

Taleghani Hospital of Tehran

taleghanihospital@sbmu.ac.ir+98 21 2243 2560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026