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Evaluation of medical therapy in improvement of hand tendons function

Evaluation of Ibuprofen therapy effect in prevent of tissue adhesion after flexor tendon repair in zone two of hand

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201301189857N2
Enrollment
60
Registered
2013-02-14
Start date
2013-01-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tendon Injury. Other contracture of tendon

Interventions

Intervention 1: Patients in interventional group will be received ibuprofen 2400 mg produced by Zahravy pharmaceutical companies in every day for a month. Intervention 2: Patients in control group wil
Treatment - Drugs
Placebo
Patients in interventional group will be received ibuprofen 2400 mg produced by Zahravy pharmaceutical companies in every day for a month.
Patients in control group will be received placebo in same shape and size similar to intervention group.

Sponsors

Vice chancellor for research Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 and 60 years. Laceration in vollar hand in zone two. Exclusion criteria: patients with cardiovascular or gastrointestinal disease, patients with previous flexor tendons injury or surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Flexor tendons function. Timepoint: Each two weeks. Method of measurement: Measurement of involved finger motion.;Tendon rupture. Timepoint: End of follow up. Method of measurement: Assay tendon motion clinically.

Secondary

MeasureTime frame
Tissue adhesion. Timepoint: End of follow up. Method of measurement: By full moving the fingers and hands.;The need for further surgery. Timepoint: End of study. Method of measurement: Limitation of motion.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Tabrizi

Tabriz University of Medical Sciences

Tabrizia@tbzmed.ac.ir+98 41 1329 7183

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026