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The evaluation of efficacy of TCA (TriChloroAcetic Acid) 33% in the treatment of lip fissure due to retinoids

The evaluation of efficacy of TCA (TriChloroAcetic Acid) 33% in compression with placebo (vaseline) in the treatment of lip fissuring due to retinoids

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201301169800N4
Enrollment
37
Registered
2013-03-27
Start date
2013-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lip fissuring. Diseases of lips

Interventions

Intervention 1: TCA usage, 4 times with weekly interval. Intervention 2: Vaselin cream applying 1 month.
Treatment - Drugs
TCA usage, 4 times with weekly interval
Vaselin cream applying 1 month

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : Patient age ranged from 18 to 70 years; contact with other topical medications would be stopped two weeks before treatment; patients who are able to read, understand and sign patient informed consent; Willing to participate in the study considering the visit requirements . Exclusion criteria: The patient had a history of contact dermatitis to the drugs; patients with acute localized infection; pregnant and lactating mothers; have OCD with digging lips habits; No satisfaction to participate at any stage of the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Healing rate based on physicians global score (0-5) after one month treatment. Timepoint: Four session with weekly period. Method of measurement: Inspection & compare the photos by dermatologist before & after treatment.

Secondary

MeasureTime frame
Patient satisfaction. Timepoint: Four session with weekly period. Method of measurement: Patient global score (0-10).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Somaih Hejazi

Shahid Beheshti Unuversity of Medical sciences

dr.s.hejazi@gmail.com+98 21 2274 1507

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026