Condition 1: Analgesia for Endoscopic Retrograde Cholangiopancreatography. Condition 2: Analgesia for Endoscopic Retrograde Cholangiopancreatography. Condition 3: Analgesia for Endoscopic Retrograde Cholangiopancreatography. Condition 4: Analgeia for colonoscopy. Condition 5: Analgeia for colonoscopy. Condition 6: Analgeia for colonoscopy. Condition 7: Analgeia for colonoscopy. Condition 8: Analgeia for colonoscopy. Cholelithiasis Cholecystitis Obstruction of bile duct Malignant neoplasm of
Conditions
Interventions
Intervention 1: In control group (group A) sedation will be induced with slow injection (in 20 sec.) of 0.1 mg/kg midazolam followed by Dextrose water 5% infusion with syring pump.Syringes will be co
Treatment - Drugs
In control group (group A) sedation will be induced with slow injection (in 20 sec.) of 0.1 mg/kg midazolam followed by Dextrose water 5% infusion with syring pump.Syringes will be covered by aluminu
In intervention group (group B) intravenous propofol with induction dose of 0.8 mg/kg followed by maintenance dose of 25 µg/kg/min through a syringe pomp.Syringes will be covered by aluminum foil.
Sponsors
Deputy of research, Shahroud University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 89 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: admitted patients for diagnostic and therapeutic colonoscopy or ERCP in gastroenterology clinic in Shahroud’s Imam Hossein hospital; 18 to 89 years old; anesthesia risk of 1, 2 or 3 (According to American society of anesthesiologist's classification). Exclusion criteria: patient refuse; under 18 and over 89 years old; anesthesia risk of 4 and 5 (According to American society of anesthesiologist's classification); a history of drug abuse; sensitivity to egg.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: before procedure and every 5 minutes during operation. Method of measurement: By Novin saadat's automatic Non invasive BP monitoring and record as mmHg.;Heart rate. Timepoint: before procedure and every 5 minutes during operation. Method of measurement: By Novin saadat's cardiac monitoring and record as beat per minute.;Respiratory rate. Timepoint: before procedure and every 5 minutes during operation. Method of measurement: BY Novin saadat's Non invasive monitoring and record as beat per minute.;O2 Saturation. Timepoint: before procedure and every 5 minutes during operation. Method of measurement: By Novin saadat's Pulse oximetery and chart as percent.;Movement. Timepoint: throughout the operation. Method of measurement: Clinical observation and chart as Yes or No.;Phonation. Timepoint: throughout the operation. Method of measurement: Clinical observation and chart as Yes or No.;Recovery time. Timepoint: Every 5 minutes during recovery. Method of measurement: The end of recovery will be determined by Modified Alderet scoring system (MASS). In this system, scoring 9 points in 5 variables of Consciousness, circulation (systemic blood pressure), breathing, SPO2, and activity, each of 2 points, specifies the end of recovery.;Endoscopist satisfaction from patient's condition. Timepoint: End of operation. Method of measurement: a five point scale (1= poor, 2= weak, 3= average, 4= good and 5 = excellent).Questionarie, chart by gastroentrologist.;The time to home readiness. Timepoint: Every 5 minutes during recovery until home readiness. Method of measurement: The time required to achieve a state of home readiness will be determined by Post Anesthesia Discharge Scoring system (PADSS). This scoring system assigned a number of 0, 1, or 2 to five variables: vital signs (pulse rate and blood pressure), activity level, nausea and vomiting, pain and surgical bleeding. Patients achieving a score of at least 9 are acceptable for discharge. char | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting. Timepoint: Throughout the recovery. Method of measurement: Clinical observation and chart as Yes or No.;Postoperative pain and agitation. Timepoint: After Procedure and every 5 minutes till discharge. Method of measurement: Questionarie and chart as Yes or No.;Awareness. Timepoint: End of recovery. Method of measurement: Questionnaire and record as Yes or No. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJavad Nourian MD
Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran
Outcome results
None listed