Evaluation of serum changes in inflammatory agents in patients with endometrioma after ethanol injection by residual method

Evaluation of changes in sera levels of interleukin 1 ß (IL-1ß), IL-6, IL-8, and anti-mullerian hormone (AMH) following ethanol sclerotherapy in patients with endometrioma using reterntion method

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130115012146N9

Enrollment

Registered

2021-11-06

Start date

2021-11-03

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis of ovary. Endometriosis of ovary

Interventions

Before any intervention, the sera levels of interleukin (IL) 1 ß, IL-6, IL-8, and antimullerian hormone would be evaluated. Then, using trans vaginal ultrasound evaluation the cyst will be detected an

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with symptomatic endometrial cysts above 3 cm Women with asymptomatic endometrial cysts above 3 cm Willingness to cooperate

Exclusion criteria

Exclusion criteria: Patients with a history of malignancy Patients with a history of inflammatory and autoimmune diseases Patients with a history of corticosteroid and immunosuppressive drugs Patients with a history of taking non-steroidal anti-inflammatory drugs for the past 7 days Patients with abnormal CEA-125 levels Patients with cysts with a volume of more than 150 ml

Design outcomes

Primary

Measure	Time frame
Evaluation of serum interleukin (IL) levels 1ß. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum IL-6 levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum IL-8 levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum AMH levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.	—

Measure

Time frame

Evaluation of serum interleukin (IL) levels 1ß. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum IL-6 levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum IL-8 levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.;Evaluation of serum AMH levels. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Blood test.

—

Secondary

Measure	Time frame
Recurrence of the cyst. Timepoint: Before the intervention and three months after the end of the intervention. Method of measurement: Vaginal ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farzadi Laaya

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026