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The effect of letrozole in reducing ß-hCG titration in ectopic pregnancies

Effect of letrozol on BHCG decrease in patients with ectopic pregnancy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130115012146N8
Enrollment
80
Registered
2021-06-12
Start date
2021-05-27
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fallopian pregnancy. Ectopic pregnancy, unspecified

Interventions

Intervention 1: Intervention group A: Methotrexate group 50 mg / m2: These people will be treated with 50 mg of methotrexate as a single dose and intramuscular injection (current common treatment). In

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Ectopic pregnancy is diagnosed and confirmed by transvaginal ultrasound and BhCG. Have a BhCG below 2500 at diagnosis. At the time of diagnosis, the size of the mass should be less than four centimeters.

Exclusion criteria

Exclusion criteria: Have indication for surgery or emergency medical treatment. Not willing to participate in the study.

Design outcomes

Primary

MeasureTime frame
Serum ßHCG level. Timepoint: On the day of treatment, the fourth, seventh and fourteenth day. Method of measurement: Blood test.

Secondary

MeasureTime frame
Hospitalization days. Timepoint: Until discharge from hospital. Method of measurement: Observations and records of patient.;Drug side effects. Timepoint: Duration of hospitalization. Method of measurement: Questionnarie.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farzadi Laaya

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026