Opium Addiction. Mental and behavioural disorders due to use of opioids
Conditions
Interventions
Intervention 1: Intervention: Methadone (each ampoule contains 10mg Methadone made by Daroopakhsh) with dosage of 0.1mg/kg injecting IV 30 minutes before induction of anesthesia. Intervention 2: contr
Treatment - Drugs
Intervention: Methadone (each ampoule contains 10mg Methadone made by Daroopakhsh) with dosage of 0.1mg/kg injecting IV 30 minutes before induction of anesthesia.
control: Morphine (each ampoule contains 10mg Morphine made by Daroopakhsh) with dosage of 0.1mg/kg injecting IV 30 minutes before induction of anesthesia.
Sponsors
Vice chancellor for research, Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria are: American Association of Anesthesiologists’ (ASA) classification of I or II; age 20 -65; having thoracic surgery (thoracotomy or incision’s extent of 10cm, without removal of rib and duration of 3 hours or less); more than 12 months history of opium addiction (inhalation form) as described by DSM-IV codes and after obtaining informed consent. Exclusion criteria are: ASA classification of 3-6 (severe systemic disorders such as Chronic Renal Failure and Chronic Heart Failure); non addicted patients; less than 12 months duration of addiction; addiction to drugs other than opium; consuming less than or more than 390mg of opium per day.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: at first, third, 6th, 12th and 24th hour of post operation time. Method of measurement: Visual Analogue Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarziyeh Khosravi
Kerman University of Medical Sciences
Outcome results
None listed