Clonidine efficacy in acute renal colic

Effect of adding oral clonidine to standard treatments on pain intensity of patients with acute renal colic

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130108012072N11

Enrollment

200

Registered

2020-10-22

Start date

2019-09-23

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute renal colic. Unspecified renal colic

Interventions

Intervention 1: Intervention group 1: 0.1 mg/kg Morphine diluted in 100 ml normal saline in 10 minutes infusion and 1 pill of 0.2 mg oral Clonidine. Intervention 2: Intervention group 2: 30 mg Ketorol

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Agreement for entering to the study No Mental Retardation Non pregnant No breast feeding Didn't use of analgesic agents since 4 hours ego No sensitivity to Morphine or Ketorolac or Clonidine Blood Pressure >=110/70 mm Hg No history of chronic liver or kidney injury VAS (Visual Analog Score)>4

Exclusion criteria

Exclusion criteria: Analgesic agents use since 4 hours ego History of drug reaction

Design outcomes

Primary

Measure	Time frame
Pain severity score with Visual Analog Scale. Timepoint: Study beginning, 20 minutes and 40 minutes after treatment. Method of measurement: Visual Analog Scale.;Drug complications. Timepoint: Study beginning, 20 minutes and 40 minutes after treatment. Method of measurement: Standard questionnaire form.	—

Secondary

Measure	Time frame
Insufficient pain control. Timepoint: 40 minutes after treatment. Method of measurement: Visual Analog Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Esmailian

Esfahan University of Medical Sciences

m_esmailian@med.mui.ac.ir+98 31 3620 2085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026