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Effectiveness and harmlessness of oral probiotic strains in the treatment of patients with plaque psoriasis in a double-blind randomized clinical trial.

Effectiveness and harmlessness of oral probiotic strains in the treatment of patients with plaque psoriasis in a double-blind randomized clinical trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130108012065N3
Enrollment
44
Registered
2023-12-25
Start date
2023-12-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Psoriasis

Interventions

Intervention 1: Intervention group: Group A of Lactocare bio-fermentable capsule drug (Lactocare), the manufacturer of Danesh Banyan Biofermentation Company, which contains bacteria (Lactobacillus rha

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All people between 18 and 70 years old Patients with plaque psoriasis who are treated with topical corticosteroids Patients with plaque psoriasis who have not received treatment with systemic drugs or at least three months have passed since the discontinuation of systemic drugs for their treatment and have not received astertine.

Exclusion criteria

Exclusion criteria: pregnancy People undergoing chemotherapy People with a history of any skin disease History of taking antibiotics in the previous 2 weeks or symptoms of bacterial infection Diagnosis of liver disease with Child-Pugh C index Renal failure with serum creatinine >1.5 mg/dl People with a history of receiving acitretin History of any type of surgery in the last 3 months

Design outcomes

Primary

MeasureTime frame
PASI Score. Timepoint: The first visit and 4 weeks later and 12 weeks after the first visit. Method of measurement: PASI score.;Patient satisfaction rate. Timepoint: It will be used after 2-3 weeks from the start of the medication until the end of the treatment process. Method of measurement: Standard questionnaire (treatment satisfaction questionnaire for Medication) TSQM.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArghavan Azizpour

Tehran University of Medical Sciences

a-azizpour@razi.tums.ac.ir+98 21 5563 0668

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026