Intranasal lidocaine effect for headache relief in patients at emergency department

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013010712050N1

Enrollment

Registered

2013-02-13

Start date

2012-12-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Headache. Condition 2: Migraine. Condition 3: headache. Headache Migraine Other headache syndromes

Interventions

Intervention 1: intervention group: one puff of 10% lidocaine spray in each nasal cavity. Intervention 2: control group: one puff of normal saline spray in each nasal cavity.

Treatment - Drugs

Placebo

intervention group: one puff of 10% lidocaine spray in each nasal cavity

control group: one puff of normal saline spray in each nasal cavity

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients with headache. Exclusion criteria: 1. History of lidocaine allergy; 2. Skull base fracture; 3. GCS<15; 4. Patients younger than 14yo; 5. Patients who received a medication in recent two hours; 6. Vital Sign instability.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: prior to and at 1, 5, 15 and 30 minutes after intervention. Method of measurement: Numeric Pain Intensity Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamadali Jafari

Shahid Sadoughi University of medical sciences

ali_jafari_25@yahoo.com ; malijafari@ssu.ac.ir+98 35 1828 4313

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026