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Replacement of sux by remifentanil in intubation (GA) in cesarean

A comparison of effect of succinylcholine and remifentanil on intubating conditions in elective cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013010612035N1
Enrollment
100
Registered
2013-07-29
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

muscle relaxant in cesarean intubation. Failed or difficult intubation

Interventions

Intervention 1: Intervention group: For induction 1mic/kg remifentanil in 30 seconds and 5mg/kg sodium thiopental in 10 seconds and N/S 5 cc are administered. After 1 min intubation is done. Interve
Treatment - Drugs
Intervention group: For induction 1mic/kg remifentanil in 30 seconds and 5mg/kg sodium thiopental in 10 seconds and N/S 5 cc are administered. After 1 min intubation is done.
Control group or sux group: For induction 5mg/kg thiopental in 10 seconds and 1.5 mg/kg sux are administered. After 30 seconds intubation is done.

Sponsors

Vice chancellor for research, Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Major inclusion criteria: Iranian pregnant female; ASA class1 and 2; 18-35 years old; BMI 18.5-24.9; without common cold; elective cesarean. Major exclusion criteria: difficult airway; significant respiratory disease; severe asthma; GERD; neurologic and neuromuscular disease; cardiovascular disease; HTN; DM; allergy to drugs used in this study; organ failure; pregnancy intoxication; GDM; Placental abruption; oligo and polyhydramnious; placental abnormalities; coagulation and fetal abnormalities; opium and alcohol abuse.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intubation conditions. Timepoint: soon after intervention. Method of measurement: upon 5 Primary outcome is devided to 3 groups as well, intermediate and bad.;APGAR. Timepoint: at min. 1 and 5 after delivery. Method of measurement: upon APGAR standard scale.

Secondary

MeasureTime frame
Jaw relaxation. Timepoint: soon after intervention. Method of measurement: upon numeric scale of jaw relaxation.;Laryngoscopy. Timepoint: 1 min. after intervention. Method of measurement: upon numeric scale of laryngoscopy.;Vocal cords. Timepoint: 1 min. after intervention. Method of measurement: upon numeric scale of vocal cords movement.;Bucking after intubation. Timepoint: 1 min after intervention. Method of measurement: upon numeric scale of bucking after intubation.;Limbs movement. Timepoint: soon after intervention. Method of measurement: upon numeric scale of limbs movement after intubation.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026