Myocardial Infarction. Acute Myocardial Infarction
Conditions
Interventions
Intervention 1: Intervention: The patients in Intervention group were adminitered to take 100 mg/kg IV bolus N-acetylcystein and then intracoronary and 10mg/kg/h over 12 hours after percutaneous coron
Prevention
Intervention: The patients in Intervention group were adminitered to take 100 mg/kg IV bolus N-acetylcystein and then intracoronary and 10mg/kg/h over 12 hours after percutaneous coronary intervention
Control: Received Standard treatment as for patients with acute myocardial infarction
Sponsors
Tehran Heart Center, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria:Myocardial infarction patients who were candidate of primary PCI . Exclusion Criteria:rescue pci; emergency for cardiac bypass ; cardiogenic shock; life expactancy less than 6 months; Age less than 18 years old; Uncontrolled hypertension; Thrombocytopenia; Malformation or aneurysm; sever chronic renal failure; Sever liver failure; treatment with glycoprotein IIb/IIIa inhibitors during PCI ; sensitivity to sulfonamides ; Major surjery; Unsatisfactory to enter to study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Troponin I. Timepoint: Baseline and after 48 hours. Method of measurement: Elisa Kit.;Hs-CRP. Timepoint: Baseline and after 48 hours. Method of measurement: Elisa Kit.;Myocardial Perfusion. Timepoint: Baseline and after Primary Percutaneous Coronary Intervention. Method of measurement: Myocardial Blush Grage and TIMI flow. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzita Hajhossein Talasaz, Mostafa Bahremand
Tehran Heart Center, Tehran University of Medical Sciences
Outcome results
None listed