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Analysis Injection of Papaverine in the Brain Vessels for to prevent some camplication of Brain bleeding

Analysis and Comparison of the Variations of Blood Flow velocity in Doppler Ultrasound of Brain Vessels before and after the Intra arterial Injection of Papaverine during the Operation of Patients Suffering from Brain Aneurysm in Al-Zahra Hospital, Isfahan, Iran during 2011-2012

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013010411996N1
Enrollment
20
Registered
2013-01-26
Start date
2011-04-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasospasm of cerebral vessels. Vasospasm of cerebral vessels

Interventions

The procedure was as follows: the qualified patients were examined under the Microvascular Doppler Ultrasound (MDS) during the operation and before the Papaverine injection
and the blood flow velocity in cerebral arteries of these patients were measured, then 200mg Papaverine, by Insulin Syringe through the main arterials of brain proximal to Aneurysm, is injected intra
Treatment - Drugs

Sponsors

Medical Univercity of Isfahan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The entrance criteria to the study included the followings: infliction to cerebral Aneurysm suffering from Sub Arachnoidhemorrhage and were candidates of surgical operation for any reason regardless of the time of hemorrhage; not being inflected to Parkinson's disease; not being in complete heart block A.V condition; not being inflicted to Glaucoma; not being pregnant and the patient`s consent. The patients that encountered brain death after the hemorrhage under Arachnoid were disregarded from the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Decrease Blood Flow velocity. Timepoint: 30 min. Method of measurement: Doppler Ultrasound sec/cm.

Secondary

MeasureTime frame
Increase Blood Flow velocity. Timepoint: 30 min. Method of measurement: Doppler Ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactghasem baghershahi

Medical Univesity of Isfahan

parsa86@yahoo.com+98 31 1668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026